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Because of the demands of these fields, professors believe that the level of rigor that is associated with general chemistry should be elevated from that of a typical introductory course. Students who are enrolled in general chemistry often desire to become doctors, researchers, and educators. Topics of general chemistry covered by the AAMC Medical College Admissions Test

General chemistry covers many of the principal foundations that apply to medicine and the human body that is essential in our current understanding and practice of medicine. In order for students to apply to medical school, they must pass the medical college admission test, or MCAT, which consists of a section covering the foundations of general chemistry. Students in colleges and universities looking to follow the " pre-medical" track are required to pass general chemistry as the Association of American Medical Colleges requires at least one full year of chemistry. The concepts taught in a typical general chemistry course are as follows: Chemistry majors as well as students across STEM majors such as biology, biochemistry, biomedicine, physics, and engineering are usually required to complete one year of general chemistry as well. These labs can consist of acid-base titrations, kinetics, equilibrium reactions, and electrochemical reactions.

The course is usually run with a concurrent lab section that gives students an opportunity to experience a laboratory environment and carry out experiments with the material learned in the course. General chemistry (sometimes referred to as "gen chem") is offered by colleges and universities as an introductory level chemistry course usually taken by students during their first year.